// Area 04 — Vaccine Development
Antigens designed,
not discovered.
Antigen design and immunogen engineering for vaccine candidates — including structure-guided design of next-generation antigens and the protein supply that development work depends on.
- We design
- Antigens & immunogens
- Method
- Structure-guided design
- We supply
- Research-grade protein
- Partners
- Research groups & institutions
// Vaccine development
Presentation is the variable.
The same antigen, presented differently, is a different candidate.
Vaccine antigens used to be found. They are now increasingly designed — stabilised in a chosen conformation, trimmed to the surface that matters, and presented in a way that produces the response you want rather than the response you happen to get.
That is a structural design problem, and it is one computational methods have changed substantially. We work on the antigen itself and on the protein supply that development work depends on.
Where we come in
- Structure-guided antigen design, including conformational stabilisation.
- Epitope focusing — presenting the surface you want the response against.
- Immunogen engineering, including scaffolding and multimeric presentation.
- Expression and stability work so the immunogen can be produced reliably.
- Research-grade protein supply through the development programme.
Working with research institutions
A large share of vaccine work sits inside universities and research institutes. We collaborate on the design side and supply the proteins, reagents and consumables the programme runs on, which removes a common source of delay.
// Capability
What we
actually do.
The specific pieces of work an engagement in this area is made of.
- 01
Antigen selection
Deciding which surface the response should be raised against, and why.
- 02
Conformational stabilisation
Locking an antigen in the state that produces the response you are after.
- 03
Epitope focusing
Trimming and shielding so the immune response goes where it is useful.
- 04
Scaffolding & presentation
Multimeric and particle presentation strategies for the immunogen.
- 05
Expression & stability
Making the designed immunogen reliably, at a yield the programme can use.
- 06
Protein supply
Research-grade proteins and reagents through the life of the programme.
// Questions
Asked
often.
If yours is not here, ask it directly — every enquiry is read by someone who can answer it.
Do you work on candidates, or only on antigen design?
Antigen and immunogen design is where our capability is strongest. We do not run immunology or clinical work — we design the protein and support the group that does.
Can you supply protein for a programme you are not designing for?
Yes. Research-grade protein, reagents and consumables can be supplied independently of any design engagement.
Is this available to institutions outside Bahrain?
Yes — we work across Saudi Arabia and the wider GCC, and with international research partners.